1 | /*
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2 | * Fragmentation.hpp
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3 | *
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4 | * Created on: Oct 18, 2011
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5 | * Author: heber
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6 | */
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7 |
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8 | #ifndef FRAGMENTATION_HPP_
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9 | #define FRAGMENTATION_HPP_
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10 |
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11 |
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12 | #ifdef HAVE_CONFIG_H
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13 | #include <config.h>
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14 | #endif
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15 |
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16 | #include "Graph/DepthFirstSearchAnalysis.hpp"
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17 |
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18 | #include "Fragmentation/fragmentation_helpers.hpp"
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19 | #include "Fragmentation/Graph.hpp"
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20 | #include "Fragmentation/HydrogenSaturation_enum.hpp"
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21 | #include "types.hpp"
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22 |
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23 | #include <map>
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24 | #include <string>
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25 | #include <vector>
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26 |
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27 | class atom;
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28 | class AtomMask_t;
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29 | class CheckAgainstAdjacencyFile;
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30 | class KeySet;
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31 | class molecule;
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32 |
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33 | class Fragmentation
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34 | {
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35 | public:
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36 | Fragmentation(molecule *_mol, CheckAgainstAdjacencyFile &_FileChecker, const enum HydrogenSaturation _saturation);
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37 | ~Fragmentation();
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38 |
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39 | int FragmentMolecule(const std::vector<atomId_t> &atomids, int Order, std::string prefix, DepthFirstSearchAnalysis &DFS);
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40 |
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41 | const Graph& getGraph() const {
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42 | return TotalGraph;
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43 | }
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44 |
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45 | private:
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46 |
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47 | void FragmentBOSSANOVA(molecule *mol, Graph &FragmentList, KeyStack &RootStack);
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48 | int GuesstimateFragmentCount(int order);
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49 |
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50 | // order at site
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51 | bool CheckOrderAtSite(AtomMask_t &AtomMask, const Graph &GlobalKeySetList, int Order, std::string path, bool LoopDoneAlready);
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52 | bool StoreOrderAtSiteFile(std::string &path);
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53 | bool ParseOrderAtSiteFromFile(const std::vector<atomId_t> &atomids, std::string &path);
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54 |
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55 | // storing fragments
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56 | void FillRootStackForSubgraphs(KeyStack &RootStack, const AtomMask_t &AtomMask);
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57 | bool AssignKeySetsToFragment(Graph &KeySetList, ListOfLocalAtoms_t &ListOfLocalAtoms, Graph &FragmentList, bool FreeList = false);
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58 | void TranslateIndicesToGlobalIDs(Graph &FragmentList, int &TotalNumberOfKeySets, Graph &TotalGraph);
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59 |
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60 | private:
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61 | //!> pointer to molecule that is fragmented
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62 | molecule *mol;
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63 | //!> whether to saturate dangling bonds with hydrogen and hence treat hydrogen special
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64 | const enum HydrogenSaturation saturation;
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65 | //!> reference to an external adjacency for comparison
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66 | CheckAgainstAdjacencyFile &FileChecker;
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67 | //!> Resulting Graph with all keysets
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68 | Graph TotalGraph;
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69 | };
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70 |
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71 |
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72 | #endif /* FRAGMENTATION_HPP_ */
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